To calculate the amount of NADPH required to make a 2 millimolar solution with a volume of 100 ml, you can use the formula:

Amount (in grams)=Concentration (in mol/L)×Volume (in L)×Molecular weight (in g/mol)

First, let's convert the concentration from millimolar (mM) to molar (M): 2 mM=2×10−3 M

The molecular weight of NADPH is approximately 744.42 g/mol.

Now, we can plug these values into the formula: Amount (in grams)=(2×10−3 M)×(100×10−3 L)×744.42 g/mol

Amount (in grams)=2×10−5×744.42 g

Amount (in grams)=0.0148884 g

Now, let's convert this amount to milligrams: 0.0148884 g×1000 mg/g=14.8884 mg

So, approximately 14.8884 milligrams of NADPH will be required to make a 2 millimolar solution with a volume of 100 ml.